What does お手上げ mean in Japanese?

お手上げ (おてあげ) means all over, given in, given up hope, bring to knees.

What JLPT level is お手上げ?

お手上げ is a JLPT N1 vocabulary word.

all over, given in, given up hope, bring to knees

お手上げ (おてあげ, oteage) is a JLPT N1 vocabulary word meaning “all over, given in, given up hope, bring to knees”.

何なにもかもが難むずかしい。お手上てあげだい。

Everything is hard. I'm throwing in the towel.

これ、私にはお手上げだよ。

This is above me.

この問題にはお手上げだ。

This problem baffles me.

まったくお手上げだ。

Everything's a little crazy right now.